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Community-Onset Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Osteomyelitis of the Pubic Symphysis
Kyung Mok Sohn1, Yeon-Sook Kim1, Shinhye Cheon1, Hyeon Jung1, Sun Hoe Koo2, and Deuk-Soo Hwang3
Departments of 1Internal Medicine, 2Laboratory Medicine, and 3Orthopedic Surgery, Chungnam National University Hospital, Daejon, Korea
Vol.43 Num.3 (p279~283)
Osteomyelitis of the pubic symphysis or pubic osteomyelitis is a rare disease entity. Predisposing factors include trauma, pelvic or urologic surgery, intravenous drug abuse, pelvic malignancy, parturition and cardiac catheterization. Pathogens vary depending on the risk factors. The most frequent causative organism is Staphylococcus aureus . Gram-negative bacteria such as Pseudomonas aeruginosa and Escherichia coli are also common pathogens. However, pubic osteomyelitis due to community-onset extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli has not previously been described. We present a patient with pubic osteomyelitis caused by ESBL-producing Escherichia coli without known predisposing factors except for diabetes.
Keywords : Osteomyelitis, Pubic symphysis, Escherichia coli , Beta-lactamases, Drug resistance