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Review Articles
Oral Agents for the Treatment of Orthopedic Infections Caused by Methicillin-resistant Staphylococci
Baek-Nam Kim
Department of Internal Medicine, Inje University College of Medicine, Busan, Korea
Vol.43 Num.4 (p322~338)
Orthopedic infections, especially implant-associated infections, are difficult to treat. Long-term oral antibiotic, along with appropriate surgery, is often needed to eradicate infections. The question still remains which antibiotic regimen is best in this setting because of a paucity of large comparative clinical trials. I reviewed in vitro and in vivo studies evaluating the effectiveness of various oral antibiotic regimens of monotherapy or combination therapy for orthopedic infections caused by methicillin-resistant staphylococci.
Keywords : Antibiotic treatment, Staphylococcus , Osteomyelitis, Infectious arthritis, Orthopedic fixation devices, Joint prosthesi