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Original Articles |
Clinical and Laboratory Characteristics of Pandemic Influenza A/H1N1 2009 Infection among Patients with Malignancy in Korea |
Hyeon Jeong Goong, Yu Ri Seo, La Young Yoon, Soon Ha Kwon, Eun Jung Lee, Min Hyok Jeon, Tae Hyong Kim, Dae Sik Hong, and Eun Ju Choo |
Department of Internal Medicine, Soonchunhyang University School of Medicine, Bucheon, Korea |
Vol.44 Num.1 (p1~4)
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Background: Patients with malignancy are considered to be at high risk of severe pandemic influenza A/H1N1 2009. This study was conducted to identify the severity of pandemic influenza A/H1N1 2009 among patients with malignancy.
Materials and Methods: Between August 2009 and December 2009, we reviewed clinical data and medical records of 31 patients with malignancy and 63 hospitalized patients without malignancy.
Results: Eighty-three patients with laboratory-confirmed pandemic influenza A/H1N1 2009 were admitted. The rate of ICU admission was higher among patients with malignancy (without malignancy 13% vs with malignancy 35%, P=0.024). The mortality rate was higher among patients with malignancy (without malignancy 6% vs with malignancy 25%, P=0.033). Patients using immunosuppressants showed a higher rate of lower respiratory tract infection (83% vs 24%, P=0.013).
Conclusions: Pandemic influenza A/H1N1 2009 in patients with malignancy was more severe than in patients without malignancy. |
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Keywords : Pandemic influenza A/H1N1 2009, Malignancy |
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