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Original Articles
Clinical and Laboratory Characteristics of Pandemic Influenza A/H1N1 2009 Infection among Patients with Malignancy in Korea
Hyeon Jeong Goong, Yu Ri Seo, La Young Yoon, Soon Ha Kwon, Eun Jung Lee, Min Hyok Jeon, Tae Hyong Kim, Dae Sik Hong, and Eun Ju Choo
Department of Internal Medicine, Soonchunhyang University School of Medicine, Bucheon, Korea
Vol.44 Num.1 (p1~4)
Background: Patients with malignancy are considered to be at high risk of severe pandemic influenza A/H1N1 2009. This study was conducted to identify the severity of pandemic influenza A/H1N1 2009 among patients with malignancy.

Materials and Methods: Between August 2009 and December 2009, we reviewed clinical data and medical records of 31 patients with malignancy and 63 hospitalized patients without malignancy.

Results: Eighty-three patients with laboratory-confirmed pandemic influenza A/H1N1 2009 were admitted. The rate of ICU admission was higher among patients with malignancy (without malignancy 13% vs with malignancy 35%, P=0.024). The mortality rate was higher among patients with malignancy (without malignancy 6% vs with malignancy 25%, P=0.033). Patients using immunosuppressants showed a higher rate of lower respiratory tract infection (83% vs 24%, P=0.013).

Conclusions: Pandemic influenza A/H1N1 2009 in patients with malignancy was more severe than in patients without malignancy.
Keywords : Pandemic influenza A/H1N1 2009, Malignancy