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A Case of Alternaria Rhinosinusitis in a Patient with Myelodysplastic Syndrome during Neutropenic Period
Ju-Yeon Heo, Yeo-Ree Yang, Jong-Wook Kim, Jae-Ki Choi, Mihee Park, Ye Jee Lim, Kyung-Wook Hong, Dong-Gun Lee, Ki-Seong Eom, and Yoo-Jin Kim
Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
Vol.44 Num.2 (p80~83)
The genus Alternaria contains several species of melanized hypomycetes that cause opportunistic human infections. The most frequent clinical manifestations of alternariosis are cutaneous and subcutaneous infections, followed by oculomycosis, invasive and non-invasive rhinosinusitis, and onychomycosis. So far, only 17 cases of rhinosinusitis caused by Alternaria species have been reported since 1977. Although several domestic cases of cutaneous alternariosis have been reported, there is no report of Alternaria rhinosinusitis in Korea. The majority of Alternaria rhinosinusitis involves immunocompromised patients. We report the first case of alternariosis in a patient with neutropenia and myelodysplastic syndrome that was treated with endoscopic debridement and a conventional antifungal agent.
Keywords : Alternaria, Sinusitis, Myelodysplastic Syndrome