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A Case of Pneumonia with Pleural Effusion Caused by Listeria monocytogenes
Tark Kim1, Dae-Young Kim1, Heungsup Sung2, Mi-Na Kim2, Sung-Han Kim1, Sang-Ho Choi1, Jun Hee Woo1, Yang Soo Kim1, and Sang-Oh Lee1
Departments of 1Internal Medicine and 2Laboratory Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Vol.44 Num.2 (p87~91)
Listeria monocytogenes is a facultative anaerobic gram positive rod bacteria that is wide spread in the natural environment and found in soil, water, decaying vegetation, and as part of the fecal flora of many mammals. It is also a common cause for meningoencephalitis and bacteremia in at-risk groups including neonates, pregnant women, elderly persons, and immunocompromised patients. However, pneumonia with pleuritis is a very rare manifestation of L. monocytogenes. We report a case of pneumonia with pleural effusion caused by L. monocytogenes as isolated from the blood culture of a patient diagnosed with acute lymphoblastic leukemia resulting from induction chemotherapy. The patient recovered after the introduction of therapeutic thoracentesis and administration of intravenous ampicillin (2 g q 6 hr ) plus gentamicin (1.7 mg/kg q 8 hr) over a two week period. This case demonstrated that L. monocytogenesis infection should be a consideration in the differential diagnosis of pneumonia and pleuritis in leukemic patients.
Keywords : Listeria monocytogenes, Pneumonia, Pleural effusion