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 Original Articles |
| Antimicrobial Susceptibility of Streptococcus pyogenes and Streptococcus agalactiae |
| Yunsop Chong, Kyungwon Lee, Oh Hun Kwon, Hyang Sook Par1 |
| Department of Clinical Pathology, Yonsei University College of Medicine, and Department of Clinical Pathology, Ewha Women's University Mokdong Hospita1, Seoul, Korea |
Vol.12 Num.2 (p111~115)
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The infections dud to S. pyogenes or S. agalactiae include serious ones requiring treatment with the most active antimicrobial agents. In this study, the susceptibility of the clinical isolates of these species were tested by an agar dilution method. All of the S. pyogenes isolates were inhibited by ≤0.008μg/ml of penicillin G, while the MIC range of tetracycline was 0.12~64μg/ml. MIC ranges against S. agalactiae were penicillin G 0.015~0.12 μg/ml, clindamycin and erythromycin 0.015-≥128μg/ml, and tetracycline 0.12~128μg/ml. MIC90s against S. agalactiae were 2~16 fold higher than those against S. pyogenes on the antimicrobial agents. The resistance rates of S. pyogenes were 2% to erythromycin and 39% to tetracycline. The rates of S. agalactiae were 1% to clindamycin, 5% to erythromycin and 90% to tetracycline. It is concluded that among the S. pyogenes and S. agalactiae strains tetracycline-resistant ones are very prevalent, but erythromycin-resistant ones are rare and β-lactam-resistant one dose not exist at present. |
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