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Original Articles
The Individual Drug Day (IDD) as a Measure of Antibiotic Usage in a University Hospital : A New Approach
Insoo Rheem, Dae Ok Choi1, Woo Sung Park1, Eun Kyoung Choi2, Hyunjoo Pai2.
Department of Clinical Pathology, Infection Control Office and QA Office1, and Division of Infectious Disease, Department of Internal Medicine2, Dankook University, College of Medicine and Hospital, Chonan, Korea
Vol.16 Num.1 (p51~60)
Background : We proposed "individual drug day (IDD)" as a unit of measurement in quantitative analysis for duration of medication therapy.

Methods : One unit of IDD is defined as one-day of duration of treatment for any prescribed drug without regard to the daily dose. In analyzing the duration of treatment the amount of an antibiotic use can be expressed by the unit of IDD or alternatively by "day(s)" and then it may be summed up individually or collectively on the purpose of analysis for a patient or a selected patient population, or for according to the class of antibiotics. We have retrospectively applied IDD to a one-month survey of the antibiotic usage for discharged patients in Dankook University Hospital in July 1997.

Results : The amount of the overall antibiotic use was 180.04 IDDs/1000 inpatients per day as of July 1997, and antibiotics were prescribed for 55.0% of inpatients over this one-month period. The Individual drug days among classes of antibiotics used was the highest in cephalosporins (52.8%, 6,103 days), followed by aminoglycosides (30.4%, 3,508 days) and penicillins (5.8%, 666 days). The ratio of prophylactic versus therapeutic antibiotic use was 3 : 1 (7,404 IDDs : 2,473 IDDs). The prophylactic use of cephalosporins was 57.3% (4,245 IDDs/7,404 IDDs), and that of aminoglycosides was 31.7% (2,347 IDDs/7,404 IDDs). Among 16 selected antibiotics, the average PDD (prescribed daily dose) of 4 antibiotics exceeded 1 DDD (defined daily dose).

Conclusions : We proposed the IDD as a measure to assess the duration and the pattern of antibiotic use.
Keywords : Antibiotics, Drug utilization, Individual drug day, Defined daily dose