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Original Articles |
Chloramphenicol Resistant Typhoid Fever |
On Sik Won, Jin Soo Kim, Choon Chu Kim, Kyung Shik Shunu, Hee Young Chung |
Department of Internal Medicine, Catholic Medical College |
Vol.5 Num.1 (p41~45)
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Chloramphenicol resistant Salmonella typhi have been reported by several authors since 1950 and ther was a large epidemic in Maxico last year.
Last summer we have experienced a small epidemic of typhoid fevor in an institution.
In 8 clinically uncontrollable cases of typhoid fever with chloramphenicol, 3 strains of Salmonella typhi were isolated and their MIC to chloramphenicol were 5~10 μg/mL.
The resistance to chloramphenicol in the isolated strains were transferred to Escherichia coli in vitro. This factor was multi-resistant.
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