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Original Articles
Chloramphenicol Resistant Typhoid Fever
On Sik Won, Jin Soo Kim, Choon Chu Kim, Kyung Shik Shunu, Hee Young Chung
Department of Internal Medicine, Catholic Medical College
Vol.5 Num.1 (p41~45)
Chloramphenicol resistant Salmonella typhi have been reported by several authors since 1950 and ther was a large epidemic in Maxico last year.
Last summer we have experienced a small epidemic of typhoid fevor in an institution.
In 8 clinically uncontrollable cases of typhoid fever with chloramphenicol, 3 strains of Salmonella typhi were isolated and their MIC to chloramphenicol were 5~10 μg/mL.
The resistance to chloramphenicol in the isolated strains were transferred to Escherichia coli in vitro. This factor was multi-resistant.

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