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A Case of Tsutsugamushi Disease Presented with Granulomatous Pleural Effusion
Kyoung Ju Ahn/Yong Joo Park/Byung Chul Lim/Kyu Hyun Lee/Jae Jung Koh/Hyung Seok Choi/Sin Eun Choi
Department of Internal Medicine, Kangnam General Hospital, Public Cooperation, Seoul, Korea. Department of Anatomical Pathology, Kangnam General Hospital, Public Cooperation, Seoul, Korea.
Vol.29 Num.4 (p327~331)
Tsutsugamushi disease is one of the acute febrile diseases caused by Orientia tsutsugamushi that is transmitted to human by the bite of larval-stage trombiculid mite (chigger). The clinical illness is characterized by abrupt onset of fever, headache, rashes, myalgia and eschar. Chest radiologic findings show reticulonodular infiltration, cardiomegaly, lymphadenopathy and in a minority, pleural effusion. About pleural effusion, it is supposed to be caused by tsutsugamushi disease itself in most cases and no case has been reported that the pleural effusion confirmed by pleural biopsy and revealed granulomatous lesions. We experienced a case of tsutsugamushi disease with pleural effusion which was also confirmed to granulomatous lesion by pleural biopsy. So we report this case with a brief review of literatures.
Keywords : Tsutsugamushi disease, pleural effusion, Granuloma