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A Case of Herpes Simlpex Meningoencephalitis with Broca's Aphasia Children over 10 Years(1986~1995)
Hyung Joon Yim/Jin Soo Lee/Byung Won Hur/Jang Wook Sohn/Heong Jeong Woo/Hee Jin Cheong/Woo Joo Kim/Min Ja Kim/Seung Chull Park
Depatment of Internal Medicine, College of Medicine, Korea University, Seoul, Korea.
Vol.31 Num.1 (p35~40)
Herpetic meningoencephalitis is a devastating disease with significant morbidity and
mortality. One of the most serious clinical sequelae is aphasia, usually of sensory type, whereas, Broca's or motor aphasia is not a commmon manifestation. We report a case of herpetic meningoencephalitis diagnosed by polymerase chain reaction (PCR) and viral culture with Broca's aphasia as a neurologic sequoia. A 35-year old male patient was admitted due to fever and altered mentality for 3 days. He was accompanied by nausea, vomiting, disorientation, and memory defect. Several vesicular eruptions were noted around the lips. Neck stiffness was present, but
Kernig's and Brudzinski signs were not observed. Herpetic meningoencephalitis was confirmed with PCR and other diagnostic tests such as EEG, brain MRI, brain CT scan, and viral culture. His overall clinical condition was improved after acyclovir therapy, but Broca's aphasia remained as a sequoia.
Keywords : Herpes simplex meningoencephalitis, Broca's aphasia